Advancing metabolic health through research and educationOPTAVIA®M

Built on decades of clinical research, our work is guided by a multidisciplinary team of scientists and experts in medical care, nutrition, exercise, biobehavioral science, and education.

Backed by over 40 years of scientific and clinical heritage

Medifast®, the company behind the Medifast Metabolic Health Institute, has a long-standing history of clinical research and scientific innovation, providing a robust foundation for our ongoing pursuit of scientific excellence.

new coach training module

Foundations of Metabolic Synchronization®

Master the breakthrough science of Metabolic Synchronization and discover how the Trilivy™ comprehensive metabolic health system is uniquely designed to support metabolic health and reverse metabolic dysfunction.* Learn how to act as a force multiplier, turning scientific breakthroughs into true metabolic health transformation.

Committed to scientific leadership

Explore highlights from our multidisciplinary team as they present clinical findings and share evidence-based insights at premier medical and nutrition conferences.

To view the full collection of posters presented by our team in 2025, please visit our dedicated research page.

*Arterburn LM, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. 2019;5(1):3-14. doi: 10.1002/osp4.312. In a clinical study, individuals on the Reset 5 & 1 Plan experienced a reduction of 14% visceral fat and 98% of lean mass was retained at 16 weeks.